4.3
Ease Adjust by Therafirm Below Knee Wrap - Unisex - Knee
Ease Adjust by Therafirm Below Knee Wrap - Regular
4.2
Medi Plus Thigh High W/ Beaded Silicone Band, Open Toe 40-50mmHg - Compression Level: Severe 40-50 MmHg - Unisex - Foot
Medi Plus Thigh High W/ Beaded Silicone Band, Open Toe 40-50mmHg - Beige
4.2
Medi Plus Knee High, Open Toe 40-50mmHg - Compression Level: Severe 40-50 MmHg - Unisex - Foot
Medi Plus Knee High, Open Toe 40-50mmHg - Beige
4.3
Medi Forte Thigh High w/ Silicone Band, Open Toe 40-50mmHg - Compression Level: Severe 40-50 MmHg - Unisex - Foot
Medi Forte Thigh High w/ Silicone Band, Open Toe 40-50mmHg - Caramel
4.4
Circaid Juxtafit Essentials Ready To Wear Armsleeve
Circaid Juxtafit Essentials Ready To Wear Armsleeve - Extra Short
4.2
Sigvaris Secure Women's Knee High 40-50mmHg - Compression Level: Severe 40-50 MmHg - Unisex - Knee
Sigvaris Secure Women's Knee High 40-50mmHg - Beige
Woman with a clipboard talking to an elderly man in a bright room.

Don't know where to start?

Take Our Compression Quiz
4.4
Sigvaris Secure Thigh High 40-50mmHg Open Toe - Compression Level: Severe 40-50 MmHg - Unisex - Foot
Sigvaris Secure Thigh High 40-50mmHg Open Toe - Beige
4.1
Sigvaris Natural Rubber Knee High, Open Toe 40-50mmHg - Compression Level: Severe 40-50 MmHg - Unisex - Foot
Sigvaris Natural Rubber Knee High, Open Toe 40-50mmHg - Beige
4.5
Medi Plus Thigh High, Open Toe 40-50mmHg - Compression Level: Severe 40-50 MmHg - Unisex - Foot
Medi Plus Thigh High, Open Toe 40-50mmHg - Beige
4.8
Medi Forte Knee High, Open Toe 40-50mmHg - Compression Level: Severe 40-50 MmHg - Unisex - Foot
Medi Forte Knee High, Open Toe 40-50mmHg - Caramel
4.7
Sigvaris Secure Knee High 40-50mmHg Open Toe - Compression Level: Severe 40-50 MmHg - Unisex - Foot
Sigvaris Secure Knee High 40-50mmHg Open Toe - Beige
4.3
Juzo Dynamic Pantyhose 40-50mmHg - Compression Level: Severe 40-50 MmHg - Female - Leg
Juzo Dynamic Pantyhose 40-50mmHg - Black
4.1
Juzo Dynamic Thigh High w/ Waist Attachment 40-50mmHg - Compression Level: Severe 40-50 MmHg - Male - Leg
Juzo Dynamic Thigh High w/ Waist Attachment 40-50mmHg - Black
4.4
Juzo Dynamic Knee High 40-50mmHg - Compression Level: Severe 40-50 MmHg - Unisex - Knee
Juzo Dynamic Knee High 40-50mmHg - Black

Want a Free Fitting?

View Stores Near You
4.0
Sigvaris Secure Men's Knee High 40-50mmHg - Compression Level: Severe 40-50 MmHg - Male - Knee
Sigvaris Secure Men's Knee High 40-50mmHg - Beige
3.9
Sigvaris Natural Rubber Thigh High W/ Waist Attachment 40-50mmHg Open Toe - Compression Level: Severe 40-50 MmHg - Male - Foot
Sigvaris Natural Rubber Thigh High W/ Waist Attachment 40-50mmHg Open Toe - Beige
4.3
Sigvaris Natural Rubber Thigh High, Open Toe 40-50mmHg - Compression Level: Severe 40-50 MmHg - Unisex - Foot
Sigvaris Natural Rubber Thigh High, Open Toe 40-50mmHg - Beige
4.2
Medi Plus Thigh High With Attachment, Open Toe 40-50mmHg Left Leg - Compression Level: Severe 40-50 MmHg - Male - Foot
Medi Plus Thigh High With Attachment, Open Toe 40-50mmHg Left Leg - Beige
4.5
Juzo Dynamic Thigh High 40-50mmHg - Compression Level: Severe 40-50 MmHg - Unisex - Leg
Juzo Dynamic Thigh High 40-50mmHg - Black
4.6
Mediven Dual Layer Knee High 40-50 mmHg - Compression Level: Severe 40-50 MmHg - Unisex - Knee
Mediven Dual Layer Knee High 40-50 mmHg - petite

Shop Severe 40-50 mmHg Online

Severe compression socks at 40-50 mmHg are the highest level of compression therapy available, designed to manage the most serious venous and lymphatic conditions. Our collection of 40-50 mmhg compression socks from specialized medical brands like Jobst, Juzo, Core-spun, Therafirm, and Sigvaris provides prescription-strength graduated compression for severe lymphedema and advanced chronic venous insufficiency. These medical-grade compression socks deliver maximum therapeutic pressure that requires professional fitting and physician oversight, ensuring you receive the intensive compression therapy your condition demands.

Which medical conditions require 40-50 mmHg compression?

Severe 40-50 mmHg compression is prescribed for advanced lymphedema (stages 2-3), severe chronic venous insufficiency with significant skin changes, and post-thrombotic syndrome with substantial swelling. This compression level is also used for managing severe varicose veins that haven't responded to lower compression grades and controlling extreme edema from various medical causes, often through men's below-the-knee and women's styles. Brands like Jobst and Sigvaris manufacture their 40-50 mmhg compression socks with reinforced construction capable of delivering these extreme pressure levels, providing the intensive therapy that severe vascular and lymphatic conditions require.

Why is a doctor's prescription mandatory for 40-50 mmHg garments?

A doctor's prescription is mandatory for severe compression socks at 40-50 mmHg because this compression level can cause serious complications if used inappropriately. Healthcare providers must evaluate your circulation, skin integrity, and overall health before prescribing medical-grade compression socks to ensure the benefits outweigh potential risks. Additionally, proper fitting by a certified fitter is essential for 40 50 mmhg compression wraps and socks from brands like Juzo and Therafirm, as incorrect sizing at this compression level can lead to dangerous pressure points or ineffective therapy, making professional medical oversight a critical safety requirement.

What is the best way to put on (don) a 40-50 mmHg compression stocking?

Donning severe 40-50 mmHg compression stockings typically requires specialized aids like donning gloves or metal donning devices due to the extreme tightness of these garments. The most effective technique involves turning the stocking inside-out to the heel, inserting your foot, then carefully rolling the fabric up your leg in small sections, a method used for both women's below-the-knee styles and thigh-highs. Brands like Sigvaris and Jobst offer compatible donning aids specifically designed for their 40-50 mmhg compression socks, and many patients find applying them first thing in the morning makes the process easier.

Can 40-50 mmHg compression be worn overnight?

No, severe 40-50 mmHg compression should not be worn overnight unless specifically prescribed by your physician for a particular medical protocol. The extreme pressure of medical-grade compression socks andcompression sleeves can restrict circulation when you're lying down, potentially causing complications rather than providing benefits during sleep. Most compression therapy protocols for 40 50 mmhg compression socks from brands like Truform and Core-spun involve wearing the garments during waking hours only, putting them on first thing in the morning and removing them before bed, unless your vascular specialist has determined that nighttime compression wear is medically necessary for your specific condition.

What is the difference between "Severe" (40-50 mmHg) and "Ultimate" (50+ mmHg) compression?

The difference between severe 40-50 mmHg and ultimate 50+ mmHg compression lies in both the pressure intensity and the extremely limited medical situations requiring compression above 50 mmHg. While severe compression socks at 40-50 mmhg are prescribed for advanced but manageable lymphedema and venous disease, ultimate compression levels above 50 mmHg are reserved for the most extreme cases of lymphedema or severe post-thrombotic syndrome. Brands like Juzo and Medi manufacture these ultra-high compression garments, including options for sport, as highly specialized medical devices requiring expert fitting and close medical monitoring.

Why Shop with Compression Health?

Compression Health specializes in providing severe medical-grade compression therapy solutions with the expertise and support that these intensive treatments require. We work closely with healthcare providers and certified fitters to ensure you receive the correct 40-50 mmHg compression products for your prescription, along with the donning aids and education needed to use them safely and effectively. Our commitment to authentic medical-grade products from trusted brands like Jobst, Sigvaris, and Juzo means you can trust that your severe compression socks meet the rigorous standards your serious medical condition demands, while our knowledgeable team remains available to support you throughout your compression therapy journey. Use Compression Health’s size charts and guide for compression brands to find your perfect fit. 

Related Categories

Diabetic Support14

Designed with graduated compression, non-binding tops, and seamless construction to improve blood flow, prevent blisters, and reduce swelling while keeping feet dry.

Lymphedema Support95

Designed with graduated compression, non-binding tops, and seamless construction to improve blood flow, prevent blisters, and reduce swelling while keeping feet dry.

Compression Therapy33

Designed with graduated compression, non-binding tops, and seamless construction to improve blood flow, prevent blisters, and reduce swelling while keeping feet dry.